Fig. 1. Serum uric acid concentration in infants fed different infant formulas or human milk. The data result from 4 separate trials as indicated by the shading. Trial A, ; infants were enrolled from birth to 8 days of age (Isomil with Iron, experimental soy formula with supplemental nucleotides 72 mg/L, human milk; n=20/group). Trial B, ; infants were enrolled from birth to 14 days of age and were fed Similac with Iron supplemented with nucleotides 72 mg/L (n=23). Trial C,; infants were enrolled from birth to 2 days of age [human milk, n=19; Similac with Iron not supplemented with nucleotides, n1=20 and n2=18 (same formula supplemented with calcium), and Enfamil with Iron, n=20]. Trial D, ; infants were enrolled between birth and 8 days of age and fed Similac with Iron not supplemented with nucleotides (n=22). Values represent mean ± SEM. Means values generated within trials were compared statistically, however, comparisons were not done across the trials constituting this Study. * No differences were detected between the groups in trial C. Means from trial A with different symbols differed, p<0.0001. Dashed lines indicate reference standards for infants 1 to 3 months of age [19].