Fig. 1A. Effect of mevastatin on the growth of mouse neuroblastoma (NBP₂) cells and rat immortalized non-tumorigenic dopamine (DA) neurons, 1 RB₃AN27 (N27) in culture. Cells were plated in a 24-well chamber and compounds were added 24 hours later. Cell viability was determined after three days of treatment. Each experiment was repeated three times with triplicate samples. Error bars are 95% confidence intervals. 1B. High performance liquid chromatography (HPLC) profile of pravastatin (P, open-ring structure) and mevastatin (M, closed-ring structure) indicating distinct peaks.