Fig. 1. Mechanisms by which EGCG may decrease energy intake, increase energy expenditure, and reduce adipose tissue mass and prevent or treat obesity and its associated diseases, diabetes and hypertension (adapted from [8]). Abbreviations: HDL, high density lipoprotein; LDL, low density lipoprotein; VLDL, very low density lipoprotein; IGF, insulin-like growth factor; CCK, cholecystokinin; GLUT4, glucose transporter 4; ACC, acetyl-CoA carboxylase; FAS, fatty acid synthase; GPDH, -glycerophosphate dehydrogenase; SCD1, stearoyl-CoA desaturase 1; HSL, hormone sensitive lipase.