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Journal of the American College of Nutrition, Vol 10, Issue 3 228-233, Copyright © 1991 by American College of Nutrition
JOURNAL ARTICLE |
M. L. Bierenbaum, R. P. Reichstein, T. R. Watkins, W. P. Maginnis and M. Geller
Kenneth L. Jordan Research Group, Montclair, New Jersey 07042.
Previous work in this laboratory had shown in a pilot study that canola oil could lower blood pressure and serum cholesterol levels. Attempting to extend this work to a larger cohort over a longer period, a 4-month study using a 30 ml/day addendum of canola oil as the replacement of the edible oils in the usual diet was undertaken in 36 hypercholesterolemic and/or hypertriglyceridemic subjects. Serum low-density-lipoprotein cholesterol (LDL-C) decreased from 173 +/- 9.0 to 160 +/- 10.0 mg/dl, p less than 0.025. Blood pressure, total cholesterol, and high-density-lipoprotein cholesterol (HDL-C) did not change significantly even though the HDL subfractions did, HDL2 decreasing and HDL3 increasing.
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