JACN Did you know that you can get alerts when a new issue is online?
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hallfrisch, J.
Right arrow Articles by Behall, K. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hallfrisch, J.
Right arrow Articles by Behall, K. M.
Journal of the American College of Nutrition, Vol. 19, No. 90003, 320S-325S (2000)
Published by the American College of Nutrition

Mechanisms of the Effects of Grains on Insulin and Glucose Responses

Judith Hallfrisch, PhD, FACN and Kay M. Behall, PhD

Diet and Human Performance Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland

Address reprint requests to: Judith Hallfrisch, Ph.D., Beltsville Agricultural Research Center-East, Building 308, Rm. 221, Beltsville, MD 20705

Consumption of a number of grains and grain extracts has been reported to control or improve glucose tolerance and reduce insulin resistance. The inability of the body to maintain normal glucose levels or to require excessive levels of insulin to do so has been called glucose intolerance, impaired glucose tolerance and insulin resistance. These conditions are associated with obesity and may be preliminary steps in the progression to type 2 diabetes mellitus. Although dietary goals recommend the consumption of three servings of whole grains per day, average consumption in the United States is less than one serving per day. There are a number of mechanisms by which grains may improve glucose metabolism and delay or prevent the progression of impaired glucose tolerance to insulin resistance and diabetes. These mechanisms are related to the physical properties and structure of grains. The composition of the grain, including particle size, amount and type of fiber, viscosity, amylose and amylopectin content all affect the metabolism of carbohydrates from grains. Increasing whole grain intake in the population can result in improved glucose metabolism and delay or reduce the risk of developing type 2 diabetes mellitus. Whole grains can provide a substantial contribution to the improvement of the diets of Americans. A number of whole grain foods and grain fiber sources are beneficial in reduction of insulin resistance and improvement in glucose tolerance. Form, amount and method of cooking of these foods as well as the health characteristics, age and gender of the group of subjects studied are all important factors in the effectiveness of the foods in altering these responses. Dietary recommendations of health organizations suggest consumption of three servings a day of whole grain foods; however, Americans generally fall below this standard. Recent research using various grains and grain products effective in improving insulin resistance or lowering glycemic index will be discussed below by possible mechanisms of action.

Key words: glucose, insulin, grains, barley, wheat, oats, glycemic index, diabetes




This article has been cited by other articles:


Home page
J. Nutr.Home page
A. Andersson, S. Tengblad, B. Karlstrom, A. Kamal-Eldin, R. Landberg, S. Basu, P. Aman, and B. Vessby
Whole-Grain Foods Do Not Affect Insulin Sensitivity or Markers of Lipid Peroxidation and Inflammation in Healthy, Moderately Overweight Subjects
J. Nutr., June 1, 2007; 137(6): 1401 - 1407.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
I. G.E. Zarraga and E. R. Schwarz
Impact of Dietary Patterns and Interventions on Cardiovascular Health
Circulation, August 29, 2006; 114(9): 961 - 973.
[Full Text] [PDF]


Home page
J. Nutr.Home page
K. Faerch, C. Lau, I. Tetens, O. B. Pedersen, T. Jorgensen, K. Borch-Johnsen, and C. Glumer
A Statistical Approach Based on Substitution of Macronutrients Provides Additional Information to Models Analyzing Single Dietary Factors in Relation to Type 2 Diabetes in Danish Adults: the Inter99 Study
J. Nutr., May 1, 2005; 135(5): 1177 - 1182.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
P. Koh-Banerjee, M. Franz, L. Sampson, S. Liu, D. R Jacobs Jr, D. Spiegelman, W. Willett, and E. Rimm
Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men
Am. J. Clinical Nutrition, November 1, 2004; 80(5): 1237 - 1245.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Coll. Nutr.Home page
K. M. Behall, D. J. Scholfield, and J. Hallfrisch
Lipids Significantly Reduced by Diets Containing Barley in Moderately Hypercholesterolemic Men
J. Am. Coll. Nutr., February 1, 2004; 23(1): 55 - 62.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Clin. Nutr.Home page
T. T Fung, F. B Hu, M. A Pereira, S. Liu, M. J Stampfer, G. A Colditz, and W. C Willett
Whole-grain intake and the risk of type 2 diabetes: a prospective study in men
Am. J. Clinical Nutrition, September 1, 2002; 76(3): 535 - 540.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Coll. Nutr.Home page
S. Liu
Intake of Refined Carbohydrates and Whole Grain Foods in Relation to Risk of Type 2 Diabetes Mellitus and Coronary Heart Disease
J. Am. Coll. Nutr., August 1, 2002; 21(4): 298 - 306.
[Abstract] [Full Text] [PDF]


Home page
J. Am. Coll. Nutr.Home page
L. Marquart, D. R. Jacobs Jr, and J. L. Slavin
Whole Grains and Health: An Overview
J. Am. Coll. Nutr., June 1, 2000; 19(90003): 289S - 290.
[Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by the American College of Nutrition.