Journal of the American College of Nutrition, Vol 8, Issue 1 69-74, Copyright © 1989 by American College of Nutrition

JOURNAL ARTICLE

Ascorbic acid, HDL cholesterol, and apolipoprotein A-I in an elderly Chinese population in Boston

G. E. Dallal, E. Choi, P. Jacques, E. J. Schaefer and R. A. Jacob
USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111.

The relationships between plasma HDL cholesterol, apolipoprotein A-I, and plasma ascorbic acid were examined in 146 women and 92 men in a Chinese population in Boston, aged 60 and above. A significant partial correlation (r = 0.21, p = 0.015) between plasma ascorbic acid and plasma HDL cholesterol was observed among (predominantly nonsmoking) females after the effects of potentially confounding variables were taken into account. A similar relationship among 26 nonsmoking men was suggestive but inconclusive; there was no evidence of a relationship among 66 male smokers. The partial correlation between plasma apolipoprotein A-I and plasma ascorbic acid was marginally significant for women (r = 0.22, p = 0.057, n = 87) but was highly significant for men (r = 0.43, p = 0.007, n = 51). The correlation coefficient for men was highly dependent on smoking status, being 0.80 for those who never smoked and almost zero for current smokers.

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