Journal of the American College of Nutrition, Vol 8, Issue 6 602-607, Copyright © 1989 by American College of Nutrition
Conditioned diminution of brain stimulation hyperphagia
S. F. Siegel
Brown University.
It is well established that electrical stimulation of the lateral
hypothalamus (ESLH) can lead to stimulus-bound feeding in many different
species. The present study examined the effect of a warning signal on
ESLH-induced feeding. When rats are warned of ESLH (through Pavlovian
conditioning), their latencies to start eating from ESLH onset are longer
(approximately 2.5X) than when they are not warned. Thus, the rats are able
to prepare for the maladaptive situation of eating when satiated.