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Journal of the American College of Nutrition, Vol 9, Issue 4 340-343, Copyright © 1990 by American College of Nutrition

JOURNAL ARTICLE

Blood and tissue zinc levels in spontaneously hypertensive rats

J. G. Henrotte, M. Santarromana, G. Franck and R. Bourdon
CNRS, Faculty of Pharmacy, University of Paris V, France.

Zinc (Zn) determinations were performed on blood plasma and red cells, liver, heart, adrenals, and spleen of spontaneously hypertensive (SHR) and control normotensive (WKY) male rats, 20 weeks of age. SHR revealed higher red cell (p = 2 x 10(-5)) and heart (p = 0.007) Zn levels than WKY rats. The water content of organs was the same in the two strains. When compared with published data, these results suggest an association between high cell Zn levels and hypertension, the meaning of which is briefly discussed.


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