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Sugar-Induced Blood Pressure Elevations Over the Lifespan of Three Substrains of Wistar Rats

Nephrology Division (H.G.P., M.Z., P.M.), Georgetown University Medical Center, Washington, DC
Department of Medicine, Georgetown University Medical Center, Washington, DC
University of Texas Medical Branch (D.P.), Galveston, Texas
Nephropathology Section (S.S.), Brookville, Maryland
Walter Reed Army Institute of Pathology, Washington DC; and (J.K.), Brookville, Maryland

View larger version (19K): [in a new window]   Fig. 1. Body weights over lifespan of SHR, WKY, and WAM. Means±SEM are depicted. Closed circles represent rats consuming High Sugar-Low Protein; closed squares represent Hi Sugar-Low Fat; stars represent baseline; open circles represent Low Sugar-High Protein; and open squares represent Low Sugar-High Fat. A minimum of nine rats per group was analyzed statistically.

View larger version (18K): [in a new window]   Fig. 2. Systolic blood pressures over lifespan of SHR, WKY, and WAM. Means±SEM are depicted. Closed circles represent rats consuming High Sugar-Low Protein; closed squares represent Hi Sugar-Low Fat; stars represent baseline; open circles represent Low Sugar-High Protein; and open squares represent Low Sugar-High Fat. A minimum of nine rats per group was analyzed statistically.