Plasma Antioxidants and Lipid Peroxidation in Acute Myocardial Infarction and Thrombolysis
Yishai Levy, MD,
Peter Bartha, MD,
Ami Ben-Amotz, PhD,
J. Gerald Brook, MD,
Gertrude Dankner,
Shai Lin, MD, PhD and
Haim Hammerman, MD
Lipid Research Unit (Y.L., P.B., J.G.B., G.D.), Haifa, ISRAEL
National Oceanographic Research Institute (A.B-A.), Haifa, ISRAEL
Department of Clinical Epidemiology (S.L.), Haifa, ISRAEL
Department of Cardiology (H.H.), Rambam Medical Center and Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, ISRAEL

View larger version (18K):
[in a new window]
|
Fig. 1. Plasma antioxidants vitamin A, E and ß-carotene in patients with AMI at baseline (0), 2 and 24 hours post STK treatment (*p<.005).
|
|

View larger version (16K):
[in a new window]
|
Fig. 2. Plasma MDA generation at baseline and after 2 hours incubation at 37°C with 100 mM AAPH. Blood was collected from patients with AMI at 0, 2 and 24 hours after treatment by thrombolysis with STK (*p<0.05).
|
|

View larger version (23K):
[in a new window]
|
Fig. 3. Baseline conjugated dienes (CD) generation related to STK treatment intervals. A) CD generation separated into 2 groups of patients who showed a peak CPK elevation before and 10 hours post STK treatment (*p<0.05). B) Correlation between peak CPK occurrence in hours and CD generation post STK treatment.
|
|
Copyright © 1998 by the American College of Nutrition.