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Effect of UV Exposure and ß-Carotene Supplementation on Delayed-Type Hypersensitivity Response in Healthy Older Men

Division of Nutritional Sciences (L.A.H., W-C.H., R.S.P., J.E.S.), Cornell University, New York
New Product Research (A.B.), SmithKline Beecham Consumer Healthcare, Parsippany, New Jersey

View larger version (17K): [in a new window]   Fig. 1. Study design. Arrows indicate duration of dietary intervention, ß-carotene or placebo treatment, and UV exposure, and X indicates times of DTH testing and blood sampling.

View larger version (36K): [in a new window]   Fig. 2. Mean plasma ß-carotene concentrations in treatment groups at baseline, pre-UV and post-UV time points.

View larger version (30K): [in a new window]   Fig. 3. Change in delayed-type hypersensitivity induration between pre-UV and post-UV time points. Values are mean±SEM.

View larger version (18K): [in a new window]   Fig. 4. Relationship between post-UV plasma ß-carotene concentration and change in delayed-type hypersensitivity induration between pre-UV and post-UV among subjects exposed to UV.

View larger version (19K): [in a new window]   Fig. 5. Relationship between post-UV plasma ß-carotene concentration and change in delayed-type hypersensitivity induration between baseline and post-UV among subjects not exposed to UV.