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L-Carnitine Improves Glucose Disposal in Type 2 Diabetic Patients

Geltrude Mingrone, MD, PhD, FACN, Aldo V. Greco, MD, Esmeralda Capristo, MD, Giuseppe Benedetti, MD, Annalisa Giancaterini, MD, Andrea De Gaetano, PhDmath and Giovanni Gasbarrini, MD

Istituto di Medicina Interna, Catholic University, Rome, ITALY



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  		Fig. 1. Mechanism of action of L-acetyl carnitine, which, through the esterification of its alcoholic groups with acetyl-CoA, shuttles acetyl groups across the mitochondria membrane. Then, the acetyl-CoAs enter the Kreb’s cycle.

 




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