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Effect of Wheat Bran on Serum Lipids: Influence of Particle Size and Wheat Protein

David JA Jenkins, MD, FACN,,, Cyril WC Kendall, PhD,,, Vladimir Vuksan, PhD,,, Livia SA Augustin, MSc,,, Christine Mehling, RD,,, Tina Parker, RD, Edward Vidgen, BSc,,, Brenda Lee, MSc,,, Dorothea Faulkner, RD, Hilda Seyler, MSc, Robert Josse, MD, Lawrence A Leiter, MD,, Philip W Connelly, PhD, and Victor Fulgoni, III, PhD

Department of Nutritional Sciences (D.J.A.J., C.W.C.K., V.V., L.S.A.A., C.M., E.V., B.L., L.A.L.), Faculty of Medicine, University of Toronto, Toronto, Ontario, CANADA
Department of Biochemistry (P.W.C.), Faculty of Medicine, University of Toronto, Toronto, Ontario, CANADA
Department of Laboratory Medicine and Pathobiology (P.W.C.), Faculty of Medicine, University of Toronto, Toronto, Ontario, CANADA
Clinical Nutrition and Risk Factor Modification Center (D.J.A.J., C.W.C.K., V.V., L.S.A.A., C.M., T.P., E.V., B.L., D.F., H.S.), St. Michael’s Hospital, Toronto, Ontario, CANADA
Department of Medicine, Division of Endocrinology and Metabolism (R.J., L.A.L., P.W.C.), St. Michael’s Hospital, Toronto, Ontario, CANADA
The Kellogg Company (V.F.), Battle Creek, Michigan



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Fig. 1. Difference from control in serum triglyceride concentration on the two wheat bran treatments, high-gluten (metabolic, n=24) and normal-gluten (ad libitum, n=24). In the metabolic study, the high-gluten high-wheat fiber treatments were associated with a mean (±SEM) reduction of 13±4% (p=0.005) in serum triglycerides which was not seen with the normal-gluten high-wheat fiber treatments in the ad libitum study (CONTRAST statement in PROC GLM/SAS [41]).

 





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