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Potential Antioxidant Effects of Zinc and Chromium Supplementation in People with Type 2 Diabetes Mellitus

Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, Beltsville, MD (R.A.A.)
LBSO, Oxidative Stress Laboratory, Joseph Fourier University, Grenoble (A.M.R.)
Laboratoires Labcatal, Montrouge Cedex (J.M.M.), FRANCE
Service d’Explorations fonctionnelle and Endocrinologie Metabolisme Hopital, Sfax (N.Z.)
Service de Medecine interne, Hopital de Monastir (S.M.)
Laboratoire de Biophysique, Faculté de Médecine (A.K.), Monastir, TUNISIA

View larger version (32K): [in a new window]   Fig. 1. Increases in plasma zinc of subjects with type 2 diabetes mellitus following daily supplementation with 30 mg of Zn as Zn gluconate for six months. Individual bars denote number of subjects with plasma zinc values in the designated intervals.

View larger version (37K): [in a new window]   Fig. 2. Plasma zinc distribution of the placebo group at the onset of the study and after six months. Individual bars denote number of subjects with plasma zinc values in the designated intervals.

View larger version (36K): [in a new window]   Fig. 3. Urinary chromium losses of the placebo group at the onset of the study and after six months. Individual bars denote the number of subjects with chromium losses in the designated intervals.