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Effect on Body Weight of Replacing Dietary Fat with Olestra for Two or Ten Weeks in Healthy Men and Women

Heli J. Roy, PhD, Marlene M. Most, PhD, Andrea Sparti, PhD, Jennifer C. Lovejoy, PhD, Julia Volaufova, PhD, John C. Peters, PhD and George A. Bray, MD

1 Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana (H.J.R., M.M.M., A.S., J.C.L., J.V., G.A.B.)
2 Regulatory and Clinical Development, The Procter & Gamble Co., Cincinnati, Ohio (J.C.P.)



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Fig. 1. Example macronutrient content of the diets for Study One.

 


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Fig. 2. Example macronutrient content of the diets for Study Two.

 


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Fig. 3. Weight loss for each participant and mean weight loss denoted with an asterisk (*) during Study One (difference from control diet).

 


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Fig. 4. Weight loss (mean ± standard error) during Study Two (difference from control diet). Between weeks 5 and 10 denoted with an asterisk (*) weight loss for control is NS and significant for reduced fat (p < 0.01) and Olestra groups (p < 0.0001).

 





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