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Calcium Absorption Varies within the Reference Range for Serum 25-Hydroxyvitamin D

Robert P. Heaney, MD, FACN, M. Susan Dowell, PhD, Cecilia A. Hale, PhD and Adrianne Bendich, PhD, FACN

Creighton University, Omaha, Nebraska (R.P.H., M.S.D.)
GlaxoSmithKline, Parsipanny, New Jersey (C.A.H., A.B.)



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Fig. 1. Time course of the incremental calcemia following ingestion of ~12.5 mmol Ca loads from two different sources and with and without pretreatment with 25OHD. The top two lines are the calcemia curves observed in participants pretreated with 25OHD, and the bottom two, those measured without vitamin D. Error bars are 1 SEM. ({square} & {triangleup} represent CitracalTM and {lozenge} & {circ} represent OscalTM.) (Copyright Robert P. Heaney, 2002. Used with permission.)

 


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Fig. 2. Time course of the mean increment in serum total calcium in two studies, in one of which vitamin D status was elevated ("D+"), and in the other, it was not ("D-"). Error bars are 1 SEM. (Copyright Robert P. Heaney, 2002. Used with permission.)

 


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Fig. 3. Correlation of AUC9 with serum 25OHD concentration in 48 measurements of calcium absorption in 34 postmenopausal women. The lines represent the least squares regression line through the data and its 95% confidence limits. (Copyright Robert P. Heaney, 2002. Used with permission.)

 





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