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Effect of Five-Year Supplementation of Vitamin C on Serum Vitamin C Concentration and Consumption of Vegetables and Fruits in Middle-Aged Japanese: A Randomized Controlled Trial

Mi Kyung Kim, PhD, Shizuka Sasazuki, MD, Satoshi Sasaki, MD, Shunji Okubo, MD, Masato Hayashi, MD and Shoichiro Tsugane, MD

Epidemiology & Biostatistics Division, National Cancer Center Research Institute East, Chiba (M.K.K., S.S., S.S., S.T.), JAPAN
Hiraka General Hospital, Yokote (S.O., M.H.), JAPAN



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Fig. 1. Profile of a randomized controlled trial.

 


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Fig. 2. Changes in serum vitamin C concentration by quartiles of serum vitamin C at baseline. The quartiles are based on the distribution of serum vitamin C concentrations at baseline by supplementation group.

 





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