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Dietary Acid-Base Balance, Bone Resorption, and Calcium Excretion

Ramina Jajoo, MD, Lingyi Song, MS, Helen Rasmussen, RD, MS, Susan S. Harris, DSc and Bess Dawson-Hughes, MD

Division of Rheumatology, Tufts-New England Medical Center (R.J.)
Bone Metabolism Laboratory (L.S., S.S.H., B.D.-H.)
Nutrition Services Department, Metabolic Research Unit (H.R.), Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts


Figure 1
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  		Fig. 1. A. Correlation between 24-hour urinary nitrogen to potassium ratio and 24-hour urinary net acid excretion (mmol/d) on day 14 (baseline) in 40 subjects (r = 0.528, P < 0.001). B. Correlation between change in the 24-hour urinary nitrogen to potassium ratio and change in 24-hour urinary net acid excretion (mmol/d) from day 14 to 74 in 40 subjects (r = 0.453, P = 0.003). Triangles represent subjects given meat and cereal food substitutes and circles represent subjects given meat and fruits and vegetables.

 

Figure 2
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  		Fig. 2. Correlation between change in urinary net acid excretion (mmol/d) and change in serum PTH (pmol/l) from day 14 to 74 in 40 subjects (r = 0.358, P = 0.023). Triangles represent subjects given meat and cereal food substitutes and circles represent subjects given meat and fruits and vegetables.

 

Figure 3
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  		Fig. 3. Correlation between change in 24-hour urinary net acid excretion (mmol/d) and change in 24-hour urinary N-telopeptide (mmol/d) from day 14 to 74 in 40 subjects (r = 0.367, P = 0.020). Triangles represent subjects given meat and cereal food substitutes and circles represent subjects given meat and fruits and vegetables.

 




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