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An Investigation of Hormone and Lipid Associations after Weight Loss in Women

School of Dietetics and Human Nutrition, McGill University, Ste-Anne-de-Bellevue
McGill University Health Center, Division of Cardiology, Montreal, Quebec, CANADA
Jean Mayer USDA HNRCA at Tufts University, Boston, Massachusetts

View larger version (25K): [in this window] [in a new window]   Fig. 1. Weekly changes in weight of individual participants throughout the study. Line shown is based on regression lines of each study period. Formulas for the regression lines are y = –0.01x + 0.22; r2 = 0.016, p > 0.05 for the pre weight loss stabilization period (days 1–15), y = –0.10x + 0.76; r2 = 0.997, p < 0.001 for the weight loss period (days 0–155), and y = 0.02x – 17.43; r2 = 0.167, p < 0.02 for the post weight loss stabilization period.

View larger version (14K): [in this window] [in a new window]   Fig. 2. Regression of in leptin (ng/L) (ß1 = –1.81; r2 = 0.35; p < 0.001), and adiponectin (mcg/L) (ß1 = 0.62; r2 = 0.19; p = 0.009) on weight loss (kg) after a 20 week period.

View larger version (21K): [in this window] [in a new window]   Fig. 3. Correlations between changes in lipid parameters and changes in hormones.