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Acute Effect of Poly-{gamma}-Glutamic Acid on Calcium Absorption in Post-Menopausal Women

Hiroyuki Tanimoto, MSc, Tom Fox, PhD, John Eagles, LRSC, Hitoshi Satoh, MSc, Hiroko Nozawa, BSc, Atsushi Okiyama, PhD, Yasushi Morinaga, PhD and Susan J. Fairweather-Tait, DSc

Institute of Food Research, Norwich Research Park, Colney (H.T., T.F., J.E.)
Diet and Health Group, School of Medicine, Health Policy and Practice, University of East Anglia (S.J.F.-T.)
Norwich Norfolk, UNITED KINGDOM, Food Research & Development Laboratories, Ajinomoto Co., Inc., Kawasaki-ku, Kawasaki, JAPAN (H.T., H.S., H.N., A.O., Y.M.)


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Fig. 1. Calcium absorption in post-menopausal women measured from a complete 24–48h urine collection after consuming 200mg Ca in orange juice with and without poly-{gamma}-glutamic acid (PGA). The significance of the difference between Ca absorption with and without PGA was evaluated by paired t-test (mean of differences = 4.5, 95% confidence intervals = 1.2 to 7.8, P = 0.0094). Each value is expressed as the Mean ± SEM.

 

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Fig. 2. The ratio of Ca absorption with PGA and without PGA was plotted against Ca absorption without PGA. The dotted line on the X-axis shows the mean value (34.6%) for Ca absorption without PGA. The solid line on the Y-axis shows the ratio of with to without PGA as 1.0.

 





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