Acute Effect of Poly-
-Glutamic Acid on Calcium Absorption in Post-Menopausal Women
Hiroyuki Tanimoto, MSc,
Tom Fox, PhD,
John Eagles, LRSC,
Hitoshi Satoh, MSc,
Hiroko Nozawa, BSc,
Atsushi Okiyama, PhD,
Yasushi Morinaga, PhD and
Susan J. Fairweather-Tait, DSc
Institute of Food Research, Norwich Research Park, Colney (H.T., T.F., J.E.)
Diet and Health Group, School of Medicine, Health Policy and Practice, University of East Anglia (S.J.F.-T.)
Norwich Norfolk, UNITED KINGDOM, Food Research & Development Laboratories, Ajinomoto Co., Inc., Kawasaki-ku, Kawasaki, JAPAN (H.T., H.S., H.N., A.O., Y.M.)

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Fig. 1. Calcium absorption in post-menopausal women measured from a complete 24–48h urine collection after consuming 200mg Ca in orange juice with and without poly- -glutamic acid (PGA). The significance of the difference between Ca absorption with and without PGA was evaluated by paired t-test (mean of differences = 4.5, 95% confidence intervals = 1.2 to 7.8, P = 0.0094). Each value is expressed as the Mean ± SEM.
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Fig. 2. The ratio of Ca absorption with PGA and without PGA was plotted against Ca absorption without PGA. The dotted line on the X-axis shows the mean value (34.6%) for Ca absorption without PGA. The solid line on the Y-axis shows the ratio of with to without PGA as 1.0.
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Copyright © 2007 by the American College of Nutrition.