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Fig. 2. Mean (±SEM) calcium retention on low calcium (LC) and high-calcium (HC) intakes in three generations of females (grandmothers, mothers, and granddaughters) from healthy (control) and osteoporotic families. Overall, balance in bone calcium turnover was significantly influenced by calcium intake (p<0.006), and was significantly higher in the granddaughters compared with grandmothers or mothers during the low-calcium period (p<0.001). Reproduced with permission of Journal of Bone and Mineral Research.