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Fig. 1. Regressions of log plasma leptin (nanograms per milliliter) vs. FM (kilograms)
a.No significant differences were noted between regression lines generated for males (SCD versus non-SCD controls). Thus, these groups are presented together. Although log plasma leptin was found to be 0.174 units lower on average with each 10-year increase in age (adjusting for SCD, gender and FM; see Table 2), for ease of presentation, age was excluded from the model in this graph and in graph 1b. No interactions involving age were significant. The regression equation for 18-year-old males is log [leptin]=1.019+0.038*SCD+0.382*(FM-15)/10.
b.Log plasma leptin concentrations were significantly greater in non-SCD control females versus males (adjusting for FM and age; p<0.0001) and significantly lower in females with SCD versus non-SCD controls (adjusting for FM and age; p<0.0001). The regression equation for 18-year-old females is log [leptin]=2.569-0.863*SCD+0.699*(FM-15)/10.
