Fig. 3. Effect of mevastatin in combination with various concentrations of individual antioxidant on the growth of mouse neuroblastoma (NBP₂) cells (A) and rat immortalized non-tumorigenic dopamine (DA) neurons (B), 1 RB₃AN27 (N27) in culture. Cells were plated in a 24-well chamber and mevastatin (25.6 µM for NB cells and 5.12 µM for N27 cells) together with various concentrations of d--tocopheryl succinate (-TS), 13-cis-retinoic acid and polar carotenoids were added immediately after one another. Cell viability was determined after three days of treatment. Each experiment was repeated three times with triplicate samples. Error bars are 95% confidence intervals (C.I.). Dotted lines show the 95% C.I. for the mevastatin response alone.

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