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Fig. 1. Flow-cytometric analysis of the effect of combination of the agents (paclitaxel, carboplatin and antioxidant mixture) on apoptosis in H520 cells. Cells were treated as described in Table 3. Shown are the histograms of a representative experiment. a) control, b) paclitaxel and carboplatin simultaneously, c) paclitaxel followed 24 hours later by carboplatin, d) antioxidant mixture and paclitaxel simultaneously followed 24 hours later by carboplatin, e) antioxidant mixture followed 24 hours later by paclitaxel and 48 hours later by carboplatin.
