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Fig. 5. This figure demonstrates the hourly mean diastolic blood pressure in volunteers with or without oral arginine supplements. ANOVA testing demonstrated a significant difference during the treatment period (Hour 5:00 to Hour 14:00, i.e., 5:00 AM to 2:00 PM). There was no difference between groups after arginine was discontinued (Hour 15:00, 16:00 and 24:00 or 0:00). Please note that the arginine was stopped at hour 14:00 or 2:00 PM. The hypotensive influence was not present one hour after stopping the arginine. Significant difference between the two groups at each time point by paired testing is indicated by a star (p < 0.05).
