Fig. 2. Changes in serum leptin concentrations in the fed state and after 24 hours of starving for interleukin-2 deficient (IL-2^-/-) and wild-type control (IL-2^+/+) male mice (10 weeks old) divided into four groups, IL-2^-/- (n = 6) and controls (n = 6), each that received anti-TNF- antibody and IL-2^-/- (n = 6), and controls (n = 6), each that did not receive anti-TNF- antibody in the fed state. Values are the means ± SEM. Means in the same nutritional state (fed, starved) with a different letter differ, p < 0.05, and all groups between fed and starved state had significant changes, p < 0.05 (ANOVA and subsequent Fisher’s protected least significant difference test).

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