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Fig. 1. Time course for the changes in plasma D-glucose (left panel) and insulin (right panel) concentrations after oral administration of D-glucose (6.9 µmol/g; closed circles and dashed line) or both D-glucose and D-fructose (3.5 µmol/g of each hexose; crosses and solid line). Control experiments are shown as open circles and solid line. Mean values (± SEM) refer to 3 (control experiments) or 4 (hexose administration) individual measurements. The incremental area under the plasma D-glucose and insulin curves averaged, after administration of D-glucose alone or together with D-fructose respectively, 413 ± 23 and 185 ± 39 mM · min and 12.31 ± 2.71 and 5.81 ± 1.21 nM · min (n = 4 in all cases).
