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Fig. 2. Adding ATP and ADP as mobile Ca2+ and Mg2+ buffers slightly shorten the action potential (9–10 s). ATP, ADP and Mg2+ not included (dash-dot line). Normal conditions: [ATP]tot 7 mM, [ADP]tot 5 µM, [Mg2+]i 1 mM (solid line). Metabolic inhibition: [ATP]tot 3 mM, [ADP]tot 3 mM, [Mg2+]i 2.25 mM (dash-dot-dot line).





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