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Fig. 1. Schematic representation of retroviral vectors used to establish an over-expressed {alpha}-synuclein (PN-54) NB cell line. PN-1 was used to generate a vector control cell line. For details see Materials and Methods. Abbreviations: LTR-long terminal repeat of murine leukemia virus; CMV-cytomegalovirus immediate early promoter; MCS-multiple cloning sites; Neo®–neomycin resistance gene; {alpha}-synuclein-human {alpha}-synuclein.





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