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Fig. 2. Twelve month changes in 20% tibia cross-section by pQCT and leg BMC by DXA in 3–5 y olds randomized to calcium supplementation or placebo and fine motor vs. gross motor exercise in a 2 x 2 factorial design. There was a significant interaction between activity and Ca supplementation in BMC (P = 0.05). There were significant (P 
0.05) activity effects in perisoteal and endosteal circumferences by pQCT and significant Ca x activity interactions for cortical area (P = 0.01) and cortical thickness (P = 0.02). Reproduced with permission from reference 22.
