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Fig. 1. Correlation between plasma vitamin E and delayed-type hypersensitivity skin response. Healthy elderly subjects were supplemented with fish oil and different levels of vitamin E for 3 mo. Plasma samples were collected to determine the vitamin E concentrations using HPLC and DTH was assessed with a Multi-Test CMI, as described in the method section. Data are the post-supplementation measures from 34 subjects. There is a significant correlation (r = 0.565, p < 0.01) between the plasma
-tocopherol concentrations and DTH responses (total maximal induration).