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The heart has been a favorite theme of artists for centuries. Leonardo Da Vinci's (1452-1519) skills in portraying the human form and its components are unsurpassed. He is considered the ultimate Renaissance man, having excelled at painting, sculpture, engineering, architecture, invention and anatomy. Diet effects on the heart have been a major focus of health research for 50 years. See the review by Hu et al. on page 5. Drawing of the Heart and its Blood Vessels, from the Anatomical Notebooks in the collection of the Biblioteca Ambrosiana, Milan, Italy.

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