|
|
||||||||
REVIEW |
Medical University of South Carolina Darby Children's Research Institute, Charleston, South Carolina
Address correspondence to: Sarah N. Taylor, M.D., MUSC Darby Children's Research Institute, 165 Ashley Avenue, P.O. Box 250917, Charleston, SC 29425. E-mail: taylorse{at}musc.edu
How human milk as the ideal infant nutrition lacks vitamin D activity leading to the severe bony deformities and muscle weakness of rickets has stymied scientists and clinicians for centuries. Recent understanding of human vitamin D requirements based on functional indicators of vitamin D activity demonstrate that the majority of humans, including lactating mothers, subsist in a vitamin D insufficient state. In this state, human milk provides inadequate vitamin D supply to the nursing infant. In contrast, with achieving maternal vitamin D sufficiency, human milk attains vitamin D activity equivalent to present infant oral supplementation. Current investigation of the role of vitamin D in diseases beyond bone health is revealing the significance of early life vitamin D sufficiency in establishing lifelong health.
Key words: human milk, lactation, infant, rickets, vitamin D
This article has been cited by other articles:
![]() |
S. N. Taylor, B. W. Hollis, and C. L. Wagner Vitamin D Needs of Preterm Infants NeoReviews, December 1, 2009; 10(12): e590 - e599. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |