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Double-Blind Controlled Study on the Effects of Dietary Diacylglycerol on Postprandial Serum and Chylomicron Triacylglycerol Responses in Healthy Humans

Hiroyuki Taguchi, MS, Hiroyuki Watanabe, PhD, Kouji Onizawa, Tomonori Nagao, MS, Naohiro Gotoh, PhD, Takuji Yasukawa, MS, Rikio Tsushima, PhD, Hiroyuki Shimasaki, PhD and Hiroshige Itakura, MD

Biological Science Laboratories, Kao Corporation (H.T., H.W., K.O., T.N., N.G., T.Y., R.T.), JAPAN
Department of Biochemistry, Teikyo University School of Medicine (H.S.), JAPAN
Division of Clinical Nutrition, The National Institute of Health and Nutrition (H.I.), JAPAN



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  		Fig. 1. Mean (± SD) changes from baseline ({Delta}) in serum triacylglycerol concentrations after ingestion of diacylglycerol emulsion (bull;) or triacylglycerol emulsion ({square}). (A) 44g fat ingestion (n = 17); (B) 20g fat ingestion (n = 10); (C) 10g fat ingestion (n = 13); a: Significantly different from fasting levels, p < 0.05 (Student’s t test for paired values); b: Significantly different from the corresponding values for the triacylglycerol emulsion, p < 0.05 (Student’s t test for paired values).

 


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  		Fig. 2. Mean (± SD) changes from baseline ({Delta}) in plasma chylomicron lipid concentrations after ingestion of diacylglycerol emulsion (bull;) or triacylglycerol emulsion ({square}) at a dose of 20g fat (n = 10). (A) Chylomicron triacylglycerol concentrations; (B) Chylomicron cholesterol concentrations; (C) Chylomicron phospholipid concentrations; a: Significantly different from fasting levels, p < 0.05 (Student’s t test for paired values), b: Significantly different from the corresponding values for the triacylglycerol emulsion; p < 0.05 (Student’s t test for paired values).

 




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