HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Vatassery, G. T. Articles by Melnyk, D. Search for Related Content PubMed PubMed Citation Articles by Vatassery, G. T. Articles by Melnyk, D.

Alpha and Gamma Tocopherols in Cerebrospinal Fluid and Serum from Older, Male, Human Subjects

Research Service (G.T.V., H.T.Q., W.E.S.), University of Minnesota, Minneapolis, Minnesota
GRECC (G.T.V., M.A.K.), University of Minnesota, Minneapolis, Minnesota
Anesthesiology Section, Surgery Service (D.M.), University of Minnesota, Minneapolis, Minnesota
Veterans Administration Medical Center, Department of Psychiatry (G.T.V., A.), University of Minnesota, Minneapolis, Minnesota
Graduate Program in Neuroscience (G.T.V.), University of Minnesota, Minneapolis, Minnesota
Department of Anesthesiology (D.M.), University of Minnesota, Minneapolis, Minnesota

View larger version (13K): [in a new window]   Fig. 1. Alpha tocopherol concentrations in serum and cerebrospinal fluid from human subjects (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection.

View larger version (14K): [in a new window]   Fig. 2. Gamma tocopherol concentrations in serum and cerebrospinal fluid from human subjects (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection.

View larger version (14K): [in a new window]   Fig. 3. The correlation between the ratios of alpha to gamma tocopherol concentrations in human serum and cerebrospinal fluid samples (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection. The ratios between the alpha and gamma tocopherol concentrations were then calculated and used in the figure.

View larger version (14K): [in a new window]   Fig. 4. The relationship between the ratio of alpha to gamma tocopherols in serum and alpha tocopherol concentrations in CSF (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection. The ratios between the alpha and gamma tocopherol concentrations were then calculated and graphed.

View larger version (14K): [in a new window]   Fig. 5. The relationship between the ratio of alpha to gamma tocopherols in serum and gamma tocopherol concentrations in CSF (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection. The ratios between the alpha and gamma tocopherol concentrations were then calculated and plotted. The data were fitted to a polynomial regression line.

View larger version (14K): [in a new window]   Fig. 6. Concentrations of alpha tocopherol in serum and gamma tocopherol in CSF of human subjects (n = 28). Samples of blood and CSF were obtained from human, male subjects, and the tocopherol concentrations were determined by HPLC with electrochemical detection.