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Phytosterols/Stanols Lower Cholesterol Concentrations in Familial Hypercholesterolemic Subjects: A Systematic Review with Meta-Analysis

School of Physiology, Nutrition and Consumer Science, North-West University, Potchefstroom, SOUTH AFRICA

View larger version (44K): [in a new window]   Fig. 1. Study Selection Process

View larger version (49K): [in a new window]   Fig. 2. Effect of phytosterol/stanol versus control on TC and LDL-C concentrations in familial hypercholesterolemic subjects. LDL-C = low-density lipoprotein cholesterol, TC = total cholesterol.

View larger version (13K): [in a new window]   Fig. 3. Effects of phytosterols/stanols on total cholesterol of familial hypercholesterolemic subjects. CI = confidence interval, N = sample size, SD = standard deviation, WMD = weighted mean difference.

View larger version (14K): [in a new window]   Fig. 4. Effects of phytosterols/stanols on low-density lipoprotein cholesterol of familial hypercholesterolemic subjects. CI = confidence interval, N = sample size, SD = standard deviation, WMD = weighted mean difference.