Influence of Long-Term Administration of Lactulose and Saccharomyces Boulardii on the Colonic Generation of Phenolic Compounds in Healthy Human Subjects
Vicky De Preter, MS,
Tamara Coopmans, BS,
Paul Rutgeerts, MD, PhD and
Kristin Verbeke, PhD
Department of Gastrointestinal Research, University Hospital Gasthuisberg, K.U. Leuven, Herestraat 49, B-3000 Leuven, Belgium
Fig. 1. Schematic representation of the study design: at the start of the study and at the end of each treatment/wash-out period the volunteers performed a test (black arrows: urine/faeces collection and evaluation of gastro-intestinal parameters).
Fig. 2. Paired scattergram of the 06 h 51Cr-EDTA excretion before (baseline) and after 4-weeks administration of lactulose (2 x 10 g/d, n = 29) expressed as % of administered dose.